Main Article Content

T.S. Romanets
F.S Bakoev
N.G. Dupliy


Limb defects in pigs have a significant genetic basis, and the identification of genes that cause predisposition to diseases can help improve the efficiency of breeding work. In this work, the prospects of using the ROBO2 gene as a candidate gene associated with the presence of bumps on the hind limbs of pigs (ZNSH) were studied. The connection of the genotypes of the ROBO2 gene with the level of average daily growth and fodder conversion in Duroc pigs was established, the most successful variants are animals with heterozygous GA genotype. The lowest level of average daily growth was found in pigs with the GG genotype, which was also associated with the presence of terminal bumps on the hind limbs. Reliable varieties found with ROBO2 gene genotypes have not been established according to the opportunistic feed version.


Download data is not yet available.


Metrics Loading ...

Article Details

Animal husbandry


Le T. H. Genome-wide association study for conformation traits in three Danish pig breeds / T.H. Le, O.F. Christensen, B. Nielsen et al. // Genetics, selection, evolution: GSE. ‒ 2017. ‒ Vol. 49. ‒ № 1. ‒ C. 12-12.

Getmantseva L. V. Assessing the Effect of SNPs on Litter Traits in Pigs / L.V. Getmantseva, S.Y. Bakoev, V.S Shevtsova et al.// Scientifica (Cairo). ‒ 2020. ‒ Vol. 2020. ‒ P. 5243689.

Колосова М. ДНК-Маркеры продуктивности в свиноводстве / М. Колосова, А. Колосов, Ф. Бакоев // Вестник Донского государственного аграрного университета. ‒ 2019. ‒ № 4‒1. ‒ P. 16-20.

Sukhno V. Association of Fut1 and Slc11a1 gene polymorphisms with productivity traits of Large White pigs / V. Sukhno, P. Vashchenko, A. Saenko et al. // Regulatory Mechanisms in Biosystems. ‒ 2022. ‒ Vol. 13. ‒ № 3. ‒ P. 225-230.

Óvilo C. SNP discovery and association study for growth, fatness and meat quality traits in Iberian crossbred pigs / C. Óvilo, N. Trakooljul, Y. Núñez et al. // Scientific reports. ‒ 2022. ‒ Vol. 12. ‒ № 1. ‒ P. 1-16.

Cao R. Genomic Signatures Reveal Breeding Effects of Lulai Pigs / R. Cao, J. Feng, Y. Xu et al. // Genes. ‒ 2022. ‒ Vol. 13. ‒ № 11. ‒ P. 1969.

Getmantseva L. Genomic Regions and Candidate Genes Linked to Capped Hock in Pig / L. Getmantseva, M. Kolosova, F. Bakoev et al. // Life. ‒ 2021. ‒ Vol. 11. ‒ № 6. ‒ P. 510.

Bovo S. Genome-wide association studies for 30 haematological and blood clinical-biochemical traits in Large White pigs reveal genomic regions affecting intermediate phenotypes / S. Bovo, G. Mazzoni, F. Bertolini et al. // Scientific reports. ‒ 2019. ‒ Vol. 9. ‒ № 1. ‒ P. 1-17.

Wang Y. An association between genetic variation in the roundabout, axon guidance receptor, homolog 2 gene and immunity traits in chickens / Y. Wang, J. Wang, B. Li et al. // Poultry Science. ‒ 2014. ‒ Vol. 93. ‒ № 1. ‒ P. 31-38.

Yue Y. Isolation and differential expression of two isoforms of the ROBO2/Robo2 axon guidance receptor gene in humans and mice / Y. Yue, B. Grossmann, D. Galetzka et al. // Genomics. ‒ 2006. ‒ Vol. 88. ‒ № 6. ‒ P. 772-778.

Hivert B. Sundaresan V. Robo1 and Robo2 are homophilic binding molecules that promote axonal growth / B. Hivert, Z. Liu, C.-Y Chuang et al. // Molecular and Cellular Neuroscience. ‒ 2002. ‒ Vol. 21. ‒ № 4. ‒ P. 534-545.